
Estradiol benzoate
CAS No. 50-50-0
Estradiol benzoate( β-Estradiol Benzoate | 17β-Estradiol 3-Benzoate | 17β-Oestradiol Benzoate | E2 Benzoate )
Catalog No. M14719 CAS No. 50-50-0
Estradiol benzoate is an estradiol analog which binds to the human, murine and chicken ERα with IC50 of 22-28 nM.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
500MG | 41 | In Stock |
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1G | 48 | In Stock |
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Biological Information
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Product NameEstradiol benzoate
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NoteResearch use only, not for human use.
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Brief DescriptionEstradiol benzoate is an estradiol analog which binds to the human, murine and chicken ERα with IC50 of 22-28 nM.
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DescriptionEstradiol benzoate is an estradiol analog which binds to the human, murine and chicken ERα with IC50 of 22-28 nM.
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In VitroCell Cytotoxicity Assay Cell Line:HFFs Concentration:0-500 μM Incubation Time:72 h Result:Inhibited HFFs at the 50% toxicity of 34.11 μM.
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In VivoAnimal Model:Ovx miceDosage:20, 100 or 200 μg/kg Administration:Subcutaneous injection (s.c.)Result:Significantly reversed the lowered uterine weight induced by Ovx.Had no obvious effects on locomotor activity in Ovx mice.Effectively reversed the changes of enlarging the width of synaptic cleft and reducing the thickness of PSD induced by Ovx.Increased the number and density of synaptic vesicles by 4-week replacement with EB (100 μg/kg).
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Synonymsβ-Estradiol Benzoate | 17β-Estradiol 3-Benzoate | 17β-Oestradiol Benzoate | E2 Benzoate
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PathwayEndocrinology/Hormones
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TargetEstrogen Receptor/ERR
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RecptormERα| hERα
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Research AreaEndocrinology
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Indication——
Chemical Information
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CAS Number50-50-0
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Formula Weight376.49
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Molecular FormulaC25H28O3
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Purity>98% (HPLC)
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SolubilityDMSO: 75 mg/mL (199.2 mM)
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SMILESO=C(OC1=CC=C2[C@@]3([H])CC[C@]4(C)[C@@H](O)CC[C@@]4([H])[C@]3([H])CCC2=C1)C5=CC=CC=C5
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Chemical Name[(8R,9S,13S,14S,17S)-17-Hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] benzoate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Matthews J, et al. J Steroid Biochem Mol Biol, 2000, 74(4), 223-234.
molnova catalog



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